Combivir (Lamivudine, Zidovudine)

What is Combivir?

Combivir (Lamivudine, Zidovudine) belongs to a group of antiviral medications that help improve the symptoms of HIV and AIDS. Containing Lamivudine and Zidovudine as active components, the treatment serves an ultimate human immunodeficiency virus drug, also known as reverse transcriptase inhibitor. Affecting the organism, the medication prevents the HIV virus from further reproduction within the body. Despite Combivir is not AIDS or HIV cure, it can decrease its symptoms.


Recommendations for Use

Take Combivir strictly following the doctor’s prescription. Otherwise, you risk experiencing severe abnormalities and health disorders. Never change the adjusted dose and duration of the treatment course. Combivir should be used daily, according to the schedule. The treatment can be administered with or without food.

To get the ultimate effect and improve HIV or AIDS symptoms successfully, one should combine Combivir treatment course with other antiviral medications, balanced diet, regular exercises and other measures. Avoid increased or doubled Combivir doses, even if you have missed one. Better skip one than take extra.

Precautions and Contraindications

Consult your doctor before Combivir intake to make sure the treatment course will be beneficial in your case and cause no side effects. Do not start the treatment course if you are allergic to Zidovudine, Lamivudine or other medications that contain the ingredients. The medication can trigger severe life-threatening complication, known as lactic acidosis. Women, overweight people and patients affected by liver diseases are more likely to experience the condition. Additionally, Combivir has been reported to lead to serious or even fatal liver disorders. Thus, inform your doctor about all the health complications you have, especially: Hepatitis B,Liver diseases,Kidney disorders,Pancreas problems, etc.

Despite the full impact of the drug on unborn and nursing children is not completely investigated yet, the drug is not recommended for pregnant and breastfeeding women. Follow all the safety instructions to prevent possible Combivir complications and severe side effects.

Drug Interactions

Provide your healthcare specialist with information about all the prescription and non-prescription drugs you take, as well as other pharmaceutical products administered to avoid dangerous interactions with Combivir. The medication should not be combined with a range of other medications, especially:

• Interferon Alfa;

• Zalcitabine;

• Ribavirin;

• Doxorubicin;

• Stavudine;

• Ganciclovir.

This is not a full list of possible Combivir interactions, thus, tell your doctor about all the treatments you take, even if they are not mentioned here.

Side Effects

As any other effective and potential medication, Combivir can lead to serious complications and new symptoms, if misused. Thus, it is essential to follow doctor’s prescription and safety instructions to avoid possible downsides. The most common Combivir side effects that are safe and temporary are:

• Nausea, vomiting and other mild stomach disorders;

• Fatigue and general weakness;

• Headache;

• Sneezing, runny nose and others.

Call your healthcare provider in case minor side effects do not disappear, though aggravate instead and trigger other, more severe health problems, especially:

• Allergic reactions;

• Muscle pain;

• Fast heart rate;

• Low level of blood cells;

• Low level of white cells;

• Liver related symptoms;

• Cold sores;

• Angina, wheezing, problems breathing;

• Diarrhea, significant weight loss, night sweats;

• Serious low back pain;

• Anxiety, depression, irritability, etc.